Merlin anticorps

N° du produit ABIN966568

Cet anticorps Lapin Polyclonal détecte spécifiquement Merlin dans IHC. Il présente une réactivité envers Humain, Souris et Rat et a été mentionné dans 3+ publications.

Aperçu rapide pour Merlin anticorps (ABIN966568)

Antigène: Merlin (NF2) (Neurofibromin 2 (NF2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Merlin est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Merlin anticorps

Specificité: Merlin (Ab-518) antibody detects endogenous levels of total Merlin protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human Merlin around the phosphorylation site of serine 518 (R-L-SP-M-E).

Information d'application

Indications d'application: WB: 1:500~1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-Merlin (ABIN966568)

Xiao, Gallagher, Shetler, Skele, Altomare, Pestell, Jhanwar, Testa: "The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression." dans: Molecular and cellular biology, Vol. 25, Issue 6, pp. 2384-94, (2005) (PubMed).

Ratner, Bryan, Weber, Nguyen, Barnes, Pitt, Gelber, Cheung, Prince: "Cystic fibrosis pathogens activate Ca2+-dependent mitogen-activated protein kinase signaling pathways in airway epithelial cells." dans: The Journal of biological chemistry, Vol. 276, Issue 22, pp. 19267-75, (2001) (PubMed).

Böhni, Hemmi, Aguet: "Signaling steps involving the cytoplasmic domain of the interferon-gamma receptor alpha-subunit are not species-specific." dans: The Journal of biological chemistry, Vol. 269, Issue 20, pp. 14541-5, (1994) (PubMed).

Détails sur Merlin

Antigène: Merlin (NF2) (Neurofibromin 2 (NF2))

Autre désignation: Merlin

Pathways: Cell-Cell Junction Organization